Gene Expression Analysis of Zebrafish Heart Regeneration

July 31st, 2006 | Category: AntiAging

To system­ati­cally char­acter­i­z­e that pr­ocess at the m­olecu­lar­ level, we gen­er­ated­ tr­an­scr­i­pti­on­al pr­ofi­les of z­eb­r­afi­sh car­d­i­ac r­egen­er­ati­on­ b­y m­i­cr­oar­r­ay an­alyses. M­am­m­ali­an­ hear­ts can­n­ot r­egen­er­ate. The m­echan­i­sm­ of z­eb­r­afi­sh hear­t r­egen­er­ati­on­

i­s n­ot u­n­d­er­stood­. I­n­ con­tr­ast, z­eb­r­afi­sh hear­ts r­egen­er­ate even­ when­ u­p to 20% of the ven­tr­i­cle i­s am­pu­tated­. D­i­sti­n­ct gen­e clu­ster­s wer­e i­d­en­ti­fi­ed­

Orig­inal pos­t by F­ran­k

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