Beliefs about controllability of Panic Disorder predict best treatment option
Moderately strong beliefs about self-control of panic disorder congruent with the cognitive intervention provided seem to moderate treatment effectiveness. They did not find a differential LOC effect for antidepressant treatment. Using the Regression Trunk Approach the researchers found that locus of control orientation (LOC) predicted the effectiveness of cognitive therapy.
A group of Dutch investigators have published a study in the May issue of Psychotherapy and Psychosomatics, which unravels the characteristics of patients who are more likely to reply to drug treatment in panic disorder. In order to analyze aptitude-treatment interactions a new strategy called the Regression Trunk Approach was used in addition to classical hierarchical multiple regression analysis. 2007;76(3):154-61.
Dusseldorp E, Spinhoven P, Bakker A, et al.
Which Panic Disorder Patients Benefit from Which Treatment: Cognitive Therapy or Antidepressants?
Psychother Psychosom.
The differential effectiveness of cognitive therapy and antidepressant treatment (paroxetine or clomipramine)
Panic frequency, agoraphobic avoidance, anxiety, depression, and disability were measured with various validated interviewer and self-report measures.
No evidence for aptitude-treatment interactions using hierarchical multiple regression analysis was found. [Abstract]
Those patients with a medium internal LOC who received cognitive therapy performed significantly better than all patients who received a placebo pill on 8 of the 10 outcome variables. Beliefs about controllability were measured with the Multidimensional Anxiety Locus of Control Scale measuring an internal, chance, therapist and medication locus of control. The researchers investigated whether similarity within patients’ beliefs about controllability of a panic disorder and the type of treatment provided predicted outcomes.
Beliefs about the controllability of a disorder may be relevant in the causation, maintenance and treatment of disorders.
Original post by Anxiety Insights
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